"Hundreds of miles" sounds bogus (I'm reminded of the claim about fluorescent lamps using an hour's worth of electricity in the first minute - not true), but the engine does wear slightly more when started first. Much of that wear is due to cold engine parts, however, and on a S&S system, the engine is warmed up and still lubricated when it restarts.
It's not like they bolted the S&S control logic onto a standard engine either: the turbo, alternator and starter motor are all specifically designed for, or differently controlled for, the Start/Stop system, and the engine control would be adapted for it too.
AlfredTI's advice is pretty much what a mechanic friend told me. Don't turn the engine off at the end of a heavy run - give it a minute to dissipate the heat out of the turbo. In some countries, where it's allowed, BMW's turbodiesel cars keep the engine turning until it reaches a safe temperature, even after the key is removed. This is a problem particulalry if you live or work in a rural area, where you're doing 50-60mph all the way to/from where you park.